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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNB2
All Species:
5.45
Human Site:
T221
Identified Species:
12
UniProt:
Q92953
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92953
NP_004761.2
911
102563
T221
T
L
P
E
L
Q
E
T
D
E
F
G
Q
L
N
Chimpanzee
Pan troglodytes
XP_528164
911
102575
T221
T
L
P
E
L
Q
E
T
D
E
F
G
Q
L
N
Rhesus Macaque
Macaca mulatta
A4K2T1
529
58315
Dog
Lupus familis
XP_543042
858
96045
L217
T
L
P
E
L
Q
S
L
D
E
F
G
Q
T
T
Cat
Felis silvestris
Mouse
Mus musculus
A6H8H5
907
102331
N221
T
L
P
E
L
Q
E
N
D
E
F
G
Q
P
S
Rat
Rattus norvegicus
Q63099
907
102077
N221
T
L
P
E
L
Q
E
N
D
E
F
G
Q
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507252
997
108259
Y211
D
L
L
A
I
L
P
Y
Y
V
T
I
F
L
T
Chicken
Gallus gallus
XP_425704
863
96938
M217
T
L
P
E
L
Q
G
M
D
E
F
G
Q
T
T
Frog
Xenopus laevis
NP_001079256
898
102391
I221
T
L
P
D
L
Q
E
I
D
E
F
G
Q
P
N
Zebra Danio
Brachydanio rerio
XP_695259
820
92072
I201
K
I
L
A
I
I
S
I
L
F
I
V
L
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195169
1105
121957
R263
T
M
E
R
L
Q
K
R
D
A
Q
N
N
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
20.8
62.9
N.A.
92.7
92.8
N.A.
46.3
63.8
70.2
63.7
N.A.
N.A.
N.A.
N.A.
38.2
Protein Similarity:
100
99.8
32.7
72
N.A.
95.3
95.3
N.A.
56.7
72.7
78.6
73.1
N.A.
N.A.
N.A.
N.A.
53.7
P-Site Identity:
100
100
0
73.3
N.A.
80
80
N.A.
13.3
73.3
80
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
0
73.3
N.A.
86.6
86.6
N.A.
20
73.3
86.6
13.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
73
0
0
0
0
0
0
% D
% Glu:
0
0
10
55
0
0
46
0
0
64
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
64
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
64
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
19
10
0
19
0
0
10
10
0
0
10
% I
% Lys:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
73
19
0
73
10
0
10
10
0
0
0
10
28
0
% L
% Met:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
0
0
10
10
0
28
% N
% Pro:
0
0
64
0
0
0
10
0
0
0
0
0
0
37
0
% P
% Gln:
0
0
0
0
0
73
0
0
0
0
10
0
64
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
0
0
0
0
0
0
10
19
% S
% Thr:
73
0
0
0
0
0
0
19
0
0
10
0
0
19
37
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _